Synthetic Metabolic Validation Library
Fully de-identified synthetic cases used to demonstrate deterministic clinical pattern behavior and safety boundaries. These cases do not represent validated real-world diagnostic performance.
Healthy Metabolic Baseline
Adult with normal glycemic, lipid, and anthropometric measurements.
Prediabetes by HbA1c
Asymptomatic adult with HbA1c in the prediabetes range.
Prediabetes by FPG
Adult with fasting plasma glucose in the impaired-fasting-glucose range.
OGTT-Only Prediabetes
Adult with isolated impaired glucose tolerance on 75-g OGTT.
Diabetes-Range Finding
Adult with HbA1c in the diabetes range without acute symptoms — requires physician confirmation.
Metabolic Syndrome with Normal Glucose
Four metabolic syndrome components present with normoglycemia.
Hyperinsulinemic Pattern with Normal Glycemic Tests
Normal glycemic tests with elevated fasting insulin and family history — sandbox-only pattern.
Acanthosis with Insufficient Lab Data
Acanthosis nigricans on exam without laboratory workup yet.
Vague Symptoms without Objective Findings
Subjective fatigue and brain-fog complaints with no objective metabolic data.
Load caseTreated State with Metformin and GLP-1
Established treatment with metformin + GLP-1 RA — interpretation modified.
Steroid-Associated Dysglycemia Context
Impaired fasting glucose during active systemic corticosteroid course.
Endurance Athlete with FPG Prediabetes Criterion
Endurance athlete meets FPG prediabetes threshold — context noted, criterion not suppressed.
Possible T1D or LADA
Symptomatic random hyperglycemia with rapid weight loss — type 1 / LADA pathway.
Hypoglycemia with Inappropriate Insulin
Documented hypoglycemia with inappropriately elevated insulin — hyperinsulinemic-hypoglycemia pathway.
Severe Hypertriglyceridemia
Triglycerides ≥500 mg/dL — pancreatitis-risk review indicated.
Very Severe Hypertriglyceridemia
Triglycerides ≥1000 mg/dL — urgent review for chylomicronemia.
HbA1c Potentially Unreliable
Documented HbA1c interference — A1C cannot serve as sole classification basis.
Pregnancy Out of Standard Runtime
Confirmed pregnancy — routed to pregnancy-specific glycemic pathway.
MASLD Cross-Trigger with FIB-4
Documented hepatic steatosis with FIB-4 ≥1.3 — hepatic pathway routing only.
Longitudinal Metabolic Deterioration
Trajectory-based composite signal — sandbox-only; production runtime emits no trend warning.
Load caseMetabolic Syndrome without Insulin Measurement
Three metabolic syndrome components met without insulin measurement available.